|
KMID : 0605620080150010046
|
|
Journal of Korean Society of Biological Psychiatry
2008 Volume.15 No. 1 p.46 ~ p.53
|
|
|
A case of Posterior Cortical Atrophy Presenting with Features of Atypical Dementia
|
|
Park Kee-Hyung
Shin Dong-Jin
Lee Yeong-Bae
Kim Sung-Wan
Park Hyeon-Mi
Sung Young-Hee
|
|
|
Abstract
|
|
|
|
Posterior cortical atrophy(PCA) is a presenile dementia that presents primarily with signs and symptoms of cortical visual dysfunction, while memory is relatively preserved until the late stage of the disease. We report a patient with PCA, confirmed by brain magnetic resonance imaging (MRI) and F18-fluorodeoxyglucose positron emission tomography(FDG PET). A 58-year-old right-handed woman presented initially with visual dimness and difficulty finding things around her. She had partial Balint’s syndrome, partial Gerstmann syndrome, and idiomotor apraxia. She also had a mild memory disturbance, but preserved insight of her disease. Neuropsychological evaluation showed decreased parietal and left temporal functions bilaterally. Brain MRI and F18-FDG PET revealed typical bilateral occipitoparietal atrophy and hypometabolism, which were slightly worse on the right side. Cholinesterase inhibitor administration for 6 months improved the memory impairment slightly, but not the cortical visual dysfunction. This is a typical case of PCA, confirmed by neurologic signs and imaging findings.
|
|
|
KEYWORD
|
|
|
Posterior cortical atrophy, Cortical visual dysfunction, Balint’s syndrome, Gerstman syndrome, Idiomotor apraxia, Occipitoparietal hypometabolism
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|